Neoplasia MCQs

The normal cellular counterparts of oncogenes are improtant for the following function, except : ( AI 2006)

Promotion of cell cycle progression
Inhibition of apoptosis
Promotion of DNA repair
Promotion of nuclear transcription

Answer

AN example of a tumor suppressor gene is : ( AI 2005)

Myc
Fos
Ras
Rb

Answer

The following is not a feature of malignant transformation by cultured cells : ( AI 2005)

Increased cell density
Increased requirement for growth factors
Alterations of cytoskeletal structures
Loss of anchorage

Answer

The correct sequence of call cycle is : ( AI 2003)

GO-GI-s-G2-M
GO-GI-G2-S-M
GO-M-G2-S-GI
GO-GI-s-m-G2

Answer

Fals about p 53 :

Present on chromosome 17
Arrest cell cycle in G1 phase
Product is a 53 k D protein
None-mutated wild p53 is associated with neoplasms in childhood

Answer

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